gliK — Aspergillus fumigatus

Summary

AFU6G09700 (symbol gliK) on Aspergillus fumigatus chromosome 6 encodes a gamma-glutamylcyclotransferase with L-glutamic cyclase activity (EC 4.3.2.9). The gene is associated with gliotoxin anabolism, regulation of gliotoxin anabolism, and inhibition of gliotoxin anabolism, as well as mycotoxin anabolism and homeostasis. The encoded product is localised to the membrane. Studies of related genes in other species link the gamma-glutamylcyclotransferase family to secondary metabolite biosynthesis pathways.