MID1 — Aspergillus fumigatus

Summary

AFU5G05840 (MID1) on chromosome 5 of Aspergillus fumigatus encodes a calcium channel subunit belonging to the Mid1/Ehs1 protein family. The gene product exhibits calcium channel activity and is localized to the plasma membrane. MID1 is associated with calcium ion import, calcium transport, and cellular homeostasis. It is linked to mating, morphogenesis, and tissue remodeling. The gene is also connected to invasive pulmonary aspergillosis, a disease studied in Mus musculus. Studies of related genes in other species link the family to acid sensitivity.