PARP — Aspergillus fumigatus
Summary
AFU5G07320 (AfPARP) encodes a poly(ADP-ribose) polymerase (PARP) family protein with NAD ADP-ribosyltransferase and protein ADP-ribosylase activities (EC 2.4.2.30). The product contains ARTD/PARP, WGR, BRCT, and catalytic domains, and binds DNA and zinc. In Aspergillus fumigatus, AfPARP is associated with apoptotic process, cell death, double-strand break repair, and sensitization, and localises to the nucleolus.
Annotations
- Chromosome
- 5
- Related genes
- PARP, parp
- GO terms
- Sensitization, Cell Death, Zn binding, DNA Binding, Nucleotidyltransferase Activity, Nucleolus, Double-strand Break Repair, Apoptotic Process
- Publications
- PMID:18689883, PMID:39555176, PMID:20045739, PMID:16510786, PMID:17559898, PMID:29980550, PMID:41752036, PMID:40974413