cprA — Aspergillus fumigatus

Summary

AFU2G07940 (cprA) on chromosome 2 of Aspergillus fumigatus encodes an NADPH--cytochrome P450 reductase, a flavoprotein with FAD- and FMN-binding domains. The gene is associated with sterol and ergosterol anabolism, detoxification, and hypersensitivity. Its product localises to the endoplasmic reticulum membrane, mitochondrial outer membrane, plasma membrane, and cytosol. Related genes in other species link the family to similar redox functions and membrane-associated electron transfer.