STI1 — Verticillium dahliae

Summary

VdSTI1 (VDAG_06242) on chromosome DS572707 of Verticillium dahliae encodes a protein containing STI1/HOP, TPR, and STI1_HS-bd domains. The product exhibits ATPase inhibitor activity, membrane insertase activity, Hsp90 binding, Hsp70 protein binding, protein serine/threonine phosphatase activity, identical protein binding, and metal binding. It is associated with posttranslational protein targeting to the ER membrane, type II transmembrane protein insertion, protein folding, protein acetylation, protein breakdown, ergosterol anabolism, signal transduction, and response to heat. The protein localizes to the TRC complex, membrane, cytoplasm, cytosol, and nucleus. VdSTI1 is associated with vascular wilt disease in cotton (Gossypium hirsutum). Related genes in other species are linked to cell cycle progression, thermotolerance, prion inheritance, nuclear import, mitochondrial transport, meiosis, cytokinesis, and chitin deposition.