CHR1 — Verticillium dahliae

Summary

VdCHR1 (VDAG_06097) on chromosome DS572707 of Verticillium dahliae encodes a DEAD-box RNA helicase with RNA helicase activity (EC 3.6.4.13), ATP binding and hydrolase activity. The gene is associated with SSU-rRNA maturation and pheromone response, and its product localises to the nucleolus and cytosol. VdCHR1 has been linked to vascular wilt in Arabidopsis thaliana. Phenotypic associations include absent vegetative growth, abnormal cell cycle progression in G1 phase, increased transposable element transposition, increased autophagy, altered RNA localization, increased desiccation resistance, decreased X-ray resistance, and abnormal nucleolar morphology. Related genes in other species link the DEAD-box helicase family to ribosome biogenesis and nuclear fusion during mating.