ABCA — Verticillium dahliae

Summary

VDAG_02913 (VdABCA) encodes a brefeldin A resistance protein belonging to the ABCG/PDR transporter family, with ATP-coupled transmembrane transporter activity, ATP hydrolase activity and ATP binding. In Verticillium dahliae, the gene is associated with response to antibiotic, xenobiotic detoxification by transmembrane export across the plasma membrane, and virus-induced PTGS. The protein localises to the plasmalemma. VdABCA is associated with plant height, leaf number, root length and drought tolerance, as well as with altered sporulation rate, cell death rate, nutrient uptake, vacuolar transport, endocytosis, mitophagy, cell cycle progression, pseudohyphal growth, and both chronological and replicative lifespan. Related genes in other species link the family to small molecule transport, alkaline pH resistance and nutrient utilisation.