NUC-1 — Verticillium dahliae

Summary

VDAG_03154 (VdNUC-1, also known as VdBHLH001) encodes a basic helix-loop-helix (bHLH) transcription factor containing a bHLH domain. The gene product exhibits RNA polymerase II transcription regulatory region sequence-specific DNA binding, protein dimerization activity, and DNA-binding transcription factor activity specific to RNA polymerase II. VdNUC-1 is associated with phosphate (Pi) homeostasis, regulation of transcription by RNA polymerase II, and DNA-dependent transcription, and localizes to the RNA polymerase II transcription regulator complex. Related genes in other species, including Verticillium nonalfalfae and various Fusarium species, are linked to similar functions, though these associations are not yet established for V. dahliae.