PGXB — Verticillium dahliae

Summary

VdPGXB (VDAG_03463) on chromosome DS572699 of Verticillium dahliae encodes an exo-polygalacturonase (EC 3.2.1.67) with exo-D-galacturonase activity, belonging to the glycosyl hydrolase family 28 (Glyco_hydro_28) and the pectin lyase fold/virulence superfamily. This extracellular enzyme is associated with pectin breakdown, cell wall organization, and carbohydrate metabolism. The gene is linked to vascular wilt disease in potato (Solanum tuberosum). Studies of related genes in other species connect the family to reduced virulence and post-harvest fruit disease, though these associations are not yet established for VdPGXB itself.