MRS1 — Verticillium dahliae

Summary

VDAG_03651 (VdMRS1, also known as MSR1) on chromosome DS572700 of Verticillium dahliae encodes an arginine--tRNA ligase (EC 6.1.1.19) with arginine-tRNA ligase activity and ATP binding, belonging to the Arg-tRNA-synth_N and DALR_anticod-bd domain families. The gene is associated with arginyl-tRNA aminoacylation, cytoplasmic and mitochondrial translation, and virus-induced post-transcriptional gene silencing. Its product localises to the mitochondrial lumen, mitochondria, and cytosol. VdMRS1 is associated with cell cycle arrest in G1 phase, decreased killer toxin resistance, reduced RNA accumulation, inviability, increased heat sensitivity, and altered chemical resistance. Related genes in other species are linked to mitochondrial genome maintenance, respiratory growth, oxidative stress resistance, and vegetative growth.