HH1 — Verticillium dahliae

Summary

VDAG_04254 (VdHH1) encodes an RNA-binding protein with RNA nuclease inhibitor activity, phase separation nucleator activity, and promoter-specific chromatin binding. It is associated with mRNA processing, splicing, polyadenylation, transport, and surveillance, as well as regulation of translation and translational initiation. The gene is linked to ethylene anabolism, spore germination, and degradation of meiosis-specific transcripts. VdHH1 localizes to the mRNA cleavage stimulating factor complex, spliceosomal complexes, stress granules, and ribosomes. Studies of related genes in other species connect the family to effector functions. In Verticillium dahliae, VdHH1 is associated with the related gene NPKA.