RRS1 — Verticillium dahliae

Summary

VDAG_04236, designated VdRRS1, encodes a protein containing a Ribosom_reg domain and is located in the nucleus, nucleolus, and preribosome large subunit precursor. In Verticillium dahliae, this gene is associated with ribosomal large subunit biogenesis, endonucleolytic cleavage of the tricistronic rRNA transcript, homologous recombination, and ribosome biogenesis. VdRRS1 is linked to numerous phenotypes including altered chemical compound accumulation, increased anaerobic growth, abnormal pseudohyphal growth, decreased pheromone sensitivity and production, absent mating response and shmoo formation, increased desiccation resistance, increased polyploidy, abnormal cytoskeleton morphology, and delayed cell cycle progression. The gene is also associated with sterile phenotype, abnormal endocytosis, increased bipolar budding, and altered nutrient uptake. Related genes in other species include MRK1, LHP1, SIR4, MAK21, and NOP2.