CDA — Verticillium dahliae

Summary

VDAG_03333, designated CDA, encodes a chitin deacetylase in Verticillium dahliae on chromosome DS572699. The product possesses chitin deacetylase activity, hydrolase activity acting on carbon-nitrogen bonds, chitin binding, and zinc/metal binding, and contains a NodB domain and a glycosyl hydrolase/deacetylase domain. CDA is associated with fungal-type cell wall biogenesis and organization, chitin and polysaccharide breakdown, carbohydrate metabolism, and immune evasion. The protein localizes to the fungal-type cell wall, plasma membrane, extracellular region, and side of membrane. Related genes in other species are linked to reduced virulence and effects on turgor pressure, though pathogenicity can also be unaffected.

Annotations

Chromosome
DS572699
Related genes
CDA, cda
GO terms
Chitin Deacetylase Activity, Zn binding, metal binding, plasmalemma, extracellular, Hydrolase Activity, Acting On Carbon-nitrogen (but Not Peptide) Bonds, Cell Wall Organization, Fungal-type Cell Wall Biogenesis
Publications
PMID:1937806, PMID:36675900, PMID:19146970, PMID:27901067, PMID:30459196, PMID:21784998, PMID:27165801, PMID:29184017
Traits
unaffected pathogenicity, reduced virulence, turgor pressure