AMT1 — Verticillium dahliae

Summary

VDAG_03160 (AMT1, also known as VdAMT1) encodes an ammonium transporter family protein containing an ammonium/urea transporter domain and an AmtB-like domain, with molecular functions including ammonium channel activity and methylammonium transmembrane transporter activity. The gene is associated with ammonium and methylammonium membrane transport, ammonium import across the plasma membrane, and secretion. It localises to the fungal-type vacuole, Golgi complex, and plasmalemma. In Verticillium dahliae, AMT1 is linked to vascular wilt disease of tomato (Solanum lycopersicum). The gene has been connected to numerous phenotypes including abnormal biofilm formation, increased virulence, increased sporulation, decreased nitrogen source utilisation, abnormal autophagy, increased necrotic cell death, and altered cell cycle progression.