GRP1 — Verticillium dahliae

Summary

VDAG_03252 (GRP1) of Verticillium dahliae encodes a glycine-rich RNA-binding protein. The product possesses poly(A), poly(U), mRNA 3′-UTR, mRNA and RNA binding activities, and is associated with mRNA processing, mRNA cis splicing via the spliceosome, cotranscriptional 3′ processing of RNA polymerase II transcripts, regulation of translation, mRNA transport, and rRNA processing. It localises to the nucleus, nucleolus, cytosol, endosome, stress granule, perinuclear region of cytoplasm, RNP, and the mRNA cleavage stimulating factor complex. Studies of related genes in other species link the GRP1 family to lethal pathogen phenotypes and invasive pulmonary aspergillosis, though these associations are not yet established in V. dahliae.