CHS3 — Verticillium dahliae

Summary

VDAG_03141, also known as VdCHS3 or CHS3, encodes a chitin synthase with chitin synthase activity (EC 2.4.1.16), placing it in the chitin synthase family. In Verticillium dahliae, this gene is associated with chitin anabolism, asexual sporulation, conidia formation, ascospore wall assembly, hyphal growth, and cellular mechanical stimulus response. It localizes to the chitosome, plasma membrane, cross wall, extracellular vesicle, and bud neck. Phenotypic associations include abnormal chitin deposition, decreased septum formation, abnormal spore wall formation, altered cell cycle progression, decreased adhesion, and increased alkaline pH resistance. The gene is linked to vascular wilt disease in cotton (Gossypium hirsutum) and Arabidopsis thaliana. Studies of related genes in other species connect the family to polysaccharide content and infection.