TPS3 — Verticillium dahliae

Summary

VDAG_02853 (VdTPS3) on chromosome DS572698 of Verticillium dahliae encodes a trehalose synthase complex regulatory subunit TPS3, possessing trehalose synthase, trehalose-phosphatase, and transglucosylase activities, and belongs to the Glyco_trans_20 and Trehalose_PPase domain families. The gene is associated with mycose biosynthesis and metabolism, penetration peg formation, ascospore formation, melanin anabolism, cellular response to heat, fungal-type cell wall organization, autophagy, and carbohydrate metabolism. It localizes to the trehalose-6-phosphate synthase complex, cytosol, and nucleus. VdTPS3 is linked to vascular wilt disease in Nicotiana benthamiana and to Verticillium dahliae. Associations with numerous cellular processes, including increased fermentative growth, altered cell cycle progression, decreased adhesion and budding, and increased flocculation and osmotic stress resistance, have been reported. Studies of related genes in other species link the family to oxidative stress response.