YPT3 — Verticillium dahliae

Summary

VdYPT3 (VDAG_00886) of Verticillium dahliae encodes a small GTPase of the Rab family, possessing GTPase activity and GTP binding. This gene is associated with the regulation of vesicle-mediated transport, intracellular protein transport, exocytosis, protein secretion, and vesicle fusion. It is linked to membrane addition at the site of cytokinesis, mitotic cytokinesis, vacuole organization, and protein localization to the cell tip and spindle pole body. VdYPT3 localizes to the transport vesicle membrane, recycling endosome, Spitzenkörper, and growing cell tip. The gene is associated with abnormal sporulation efficiency, delayed vegetative growth, decreased cell cycle progression, increased polyploidy and aneuploidy, altered vesicle distribution, and abnormal Golgi morphology.