GRP2 — Verticillium dahliae

Summary

VDAG_01126 (GRP2) in Verticillium dahliae encodes a D-lactaldehyde dehydrogenase with ketoreductase and NAD(P)-dependent oxidoreductase activity, belonging to the NAD(P)_dehydrat-like and epimerase_deHydtase families. The gene is associated with lactate anabolism from pyruvate, methylglyoxal metabolism, and the biosynthesis of fumonisin, novofumigatonin, and terpenoids. Its product localises to the cytoplasm, cytosol, nucleus, extracellular space, and fungal biofilm matrix. Related genes in other species are linked to EC 1.1.1.283 and broader oxidoreductase functions.

Annotations

Chromosome
DS572696
Related genes
GRP2
GO terms
Nucleus, Cytoplasm, Ketoreductase Activity, Cytosol, extracellular, terpenoid anabolism, Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor, lactaldehyde dehydrogenase (NADP+)
Publications
PMID:17419877, PMID:15378761, PMID:12620260, PMID:29968715, PMID:28529508, PMID:15969533, PMID:12720383, PMID:20569311