RFX1 — Verticillium dahliae

Summary

VdRFX1 (VDAG_01397) of Verticillium dahliae encodes a DNA-binding transcription factor of the RFX family, with both activator and repressor activities annotated. It localises to the nucleus, cytoplasm and chromatin. The gene is associated with regulation of transcription by RNA polymerase II, including positive regulation, and with DNA-dependent transcription. It is associated with hyphal growth, the DNA damage response and downregulation of cell adhesion. Related genes in other species link the family to turgor pressure. Sequence similarity places VdRFX1 within a broader group of RFX-like proteins found across related species.