HH1 — Verticillium dahliae

Summary

VdHH1 (VDAG_01787) in Verticillium dahliae encodes a protein containing WH1/EVH1 and WH2 domains, with molecular functions including Arp2/3 complex binding, G-actin binding, and actin binding. The gene is associated with actin filament branching and nucleation, actin cortical patch assembly, mitotic actomyosin contractile ring assembly, mitotic cytokinesis, spore germination, establishment or maintenance of cell polarity, endocytosis, and ethylene anabolism. It localizes to the medial ring, actin patch, and mating projection tip. Studies of related genes in other species link the family to additional domains such as histone H1/H5 and vesicle transport v-SNARE N-terminal domains, though these associations are not established for VdHH1 itself.