ILV6 — Verticillium dahliae

Summary

VdILV6 (VDAG_01958) on chromosome DS572697 of Verticillium dahliae encodes the small regulatory subunit of acetolactate synthase, an enzyme complex with acetolactate synthase regulator activity and acetolactate synthase activity. The gene is associated with branched-chain amino acid biosynthesis, including valine, isoleucine, and leucine anabolism, and with morphogenesis. The encoded protein localises to the acetolactate synthase complex, cytoplasm, and mitochondrial nucleoid. VdILV6 has been linked to numerous phenotypes including abnormal colony color, decreased fermentative and respiratory metabolism, increased cell death, abnormal cytokinesis, altered cell cycle progression, decreased osmotic stress resistance, absent sporulation, abnormal actin cytoskeleton and mitochondrial morphology, decreased telomere length, and altered cell size. Related genes in other species are linked to abnormal chemical compound accumulation and vacuolar morphology.