MAP1 — Verticillium dahliae

Summary

VDAG_01770 (VdMAP1, also known as VdMCM1) on chromosome DS572697 of Verticillium dahliae encodes a MADS-box transcription factor of the SRF-like family, with DNA-binding, bending, and RNA polymerase II-specific transcription activator activity. The gene is associated with responses to nitrate and other stresses, secondary metabolism, secretion, cell adhesion, and filamentous growth. It is linked to penetration peg formation, pseudohyphal growth regulation, and L-serine biosynthesis. Phenotypic associations include abnormal mating and pheromone sensitivity, decreased cell fusion, altered cell cycle progression, and loss of hyperosmotic stress resistance. The gene product localises to the nucleus and chromatin. Studies of related genes in other species link the family to loss of pathogenicity and salt response.