PAP1 — Verticillium dahliae

Summary

VDAG_01588, also known as VdPAP1, encodes a bZIP transcription factor of the AP-1-like family, possessing DNA-binding transcription activator activity and the ability to bind nucleosomes and cis-regulatory regions. In Verticillium dahliae, this gene is associated with the regulation of , including the anabolism of emericellin, shamixanthone, and sterigmatocystin, as well as the inhibition of asperthecin formation. VdPAP1 is linked to cellular responses to oxidative stress, lipid oxidation, and cadmium, and is connected to both asexual and sexual sporulation, apoptotic processes, and immune evasion. The gene product localizes to the nucleus, cytoplasm, and chromatin, and is part of transcription regulator complexes. Studies of related genes in other species link the family to oxidative stress response and calcium sensitivity.