ABCA — Verticillium dahliae

Summary

VDAG_01167, designated VdABCA, encodes an ABC transporter of the ABCG/PDR subfamily, possessing ATP hydrolase activity and ATP-binding capacity. In Verticillium dahliae, this gene is associated with xenobiotic detoxification via transmembrane export across the plasma membrane, response to toxic substances, virus-induced post-transcriptional gene silencing, and the zearalenone biosynthetic process. The protein localises to both the vacuolar membrane and the plasmalemma. VdABCA is associated with plant height, leaf number, root length, and drought tolerance. Studies of related genes in other species connect the family to altered virulence, including hypervirulence and reduced virulence, as well as to oxidative stress response and associations with fusarium head blight and invasive pulmonary aspergillosis.