CP1 — Verticillium dahliae

Summary

VDAG_01262 (VdCP1) on chromosome DS572696 of Verticillium dahliae encodes a serine carboxypeptidase belonging to the peptidase S10 and alpha/beta hydrolase families. The gene is associated with proteolysis, methylation, and secretion, and its product localises to the fungal-type vacuole, plasmalemma, and side of membrane. VdCP1 has been connected to numerous cellular processes including abnormal autophagy, cytokinesis, endocytosis, Golgi morphology, nuclear fusion during mating, and altered cell death responses. It is also linked to changes in acquired thermotolerance, prion inheritance, ribophagy, mitophagy, pexophagy, and replicative lifespan. Related genes in other species associate the family with apoplastic effector function and carboxypeptidase activity (EC 3.4.16.5/6), though these specific roles are not established for VdCP1 itself.