RTT109 — Neurospora crassa

Summary

NCU09825 (RTT109) in Neurospora crassa encodes a histone acetyltransferase with histone H3K56 acetyltransferase activity, classified as EC 2.3.1.48, and belongs to the Rtt109/CBP and HAT_RTT109-like domain families. The gene is associated with memory, nucleosome assembly, cell cycle checkpoint, regulation of DNA-templated transcription, homologous recombination, mitosis, DNA damage response, methylation, DNA repair, and cell cycle processes. Its product localizes to the vacuole, chromatin, and nucleus. Related genes in other species link the RTT109 family to histone acetylation functions, though these associations are not directly established for N. crassa.