fsd-1 — Neurospora crassa

Summary

NCU09915, also known as fsd-1, encodes a fungal transcriptional regulator with an NDT80 DNA-binding domain and a p53-like transcription factor DNA-binding superfamily domain, functioning as a DNA-binding transcription factor. In Neurospora crassa, this gene is associated with protoperithecium formation, meiosis, the meiotic cell cycle, and positive regulation of transcription by RNA polymerase II. It is also linked to phospholipid and melanin anabolism, and localizes to the nucleus and nuclear chromosome. Studies of related genes in other species connect the family to virulence and pathogenicity, though these associations are not established for N. crassa.