PHO89 — Neurospora crassa

Summary

NCU09564 (PHO89, pho-4) on Neurospora crassa chromosome 7 encodes a sodium:phosphate symporter, a member of the Phos_transporter family. The gene is associated with phosphate ion membrane transport, sulfate assimilation, and embryogenesis, and its product localises to the plasmalemma. PHO89 is associated with numerous phenotypes, including decreased phosphorus source utilisation, absent nutrient uptake, altered cold sensitivity, increased vegetative growth and exponential-phase growth rate, increased prion formation and loss, increased autophagy, abnormal cell cycle progression and G1 arrest, abnormal cell and bud morphology, decreased sporulation and sporulation efficiency, increased telomere length, abnormal nucleolar morphology and size, abnormal lipid particle morphology, increased colony sectoring, increased stress resistance, and increased protein activity. The gene is also connected to related phosphate transporters such as PHO-4, PHO91, PHO87, and PHO90.