gh5-1 — Neurospora crassa

Summary

NCU09524 (gh5-1) on Neurospora crassa chromosome 3 encodes a CBM1 domain-containing protein with cellulose 1,4-beta-cellobiosidase, endo-1,4-beta-xylanase, and cellulase activities, as well as cellulose binding. This extracellular enzyme is associated with xylan, glucan, and cellulose breakdown, and with carbohydrate metabolism. Studies of related genes in other species link the family to cellulase and xylanase functions (EC 3.2.1.4, 3.2.1.8, 3.2.1.91) and to unaffected pathogenicity and fusarium head blight, though these associations are not established for N. crassa.