RAS1 — Neurospora crassa

Summary

NCU03616 (RAS1) on Neurospora crassa chromosome 5 encodes a small GTPase of the Ras-type family with GTPase activity, GTP binding and G protein activity. It is associated with Ras protein signal transduction, regulation of conidium formation, mating type switching, spore germination, pheromone response, cell polarity establishment, invasive growth, meiosis, hyphal growth, mating, morphogenesis, cell death, autophagy, filamentous growth and cell localisation. The gene is linked to the plasmalemma. Phenotypic associations include decreased vacuolar transport rate, absent bipolar budding pattern, decreased redox state, increased mating type switching, decreased entry into G0, absent osmotic and oxidative stress resistance, delayed nuclear export, abnormal pheromone production, increased protein transport, delayed cell cycle progression in telophase, absent prion inheritance, increased recovery from pheromone-induced cell cycle arrest, decreased budding rate, decreased flocculation and absent transposable element transposition.