cwc15 — Neurospora crassa

Summary

NCU00335 (cwc15) on Neurospora crassa chromosome 3 encodes a pre-mRNA-splicing factor cwc15, a member of the Cwf_Cwc_15 protein family, and is annotated with RNA binding molecular function. The gene is associated with mRNA splicing via the spliceosome, including cis splicing, as well as vacuolar protein sorting. Its product localizes to the nucleus, the Prp19 complex, the catalytic step 2 spliceosome, and post-mRNA release spliceosomal complexes. Studies of related genes in other species link the family to spliceosome function, though these associations are not directly established for N. crassa.