CAT1 — Neurospora crassa

Summary

NCU00355 (CAT1, cat-3) on Neurospora crassa chromosome 3 encodes a clade 2 catalase with catalase activity (EC 1.11.1.6), heme binding and metal binding. The gene is associated with the hydrogen peroxide catabolic process, cellular response to hydrogen peroxide, response to oxidative stress, response to superoxide, heme oxidation, protein oxidation, and cellular responses to heat and iron ion starvation. It is linked to carotene anabolism, regulation of growth, asexual sporulation, conidia formation, cell differentiation, nonsense-mediated mRNA decay, spindle assembly and the spindle assembly checkpoint, and chromatin silencing. The encoded protein localises to the peroxisomal lumen, cytosol, ascospore wall, and extracellularly.