PDEB — Neurospora crassa

Summary

NCU00478 (PDEB, also known as acon-2) on Neurospora crassa chromosome 3 encodes a phosphodiesterase with cGMP and cAMP-specific phosphodiesterase activity, containing a PDEase catalytic domain and HD/PDEase domain, and binds metal ions. The gene is associated with negative regulation of cAMP/PKA signaling, signal transduction, regulation of gene expression, and developmental processes including developmental induction, circadian rhythm, conidiophore development, asexual sporulation, sporulation, and morphogenesis. Related genes in other species, such as Fusarium oxysporum and Verticillium dahliae, share sequence similarity with this phosphodiesterase family.