SHO1 — Magnaporthe oryzae 70-15

Summary

MGG_09125 (SHO1, also known as MoSHOA, MoSHO1, SSU81, MoSSU81) in Magnaporthe oryzae 70-15 encodes a protein containing an SH3 domain characteristic of the Sho1 family. The gene is associated with the plasma membrane and linked to diverse biological processes including signal transduction, appressorium formation, host invasion, endocytosis, autophagy, filamentous growth, and regulation of actin polymerization. It is also connected to receptor internalization, protein phosphorylation, secretion, morphogenesis, and intracellular transport. Phenotypic associations include absent osmotic, oxidative, and alkaline pH stress resistance, decreased cell cycle progression and endocytosis, abnormal filamentous growth and flocculation, increased adhesion and mating efficiency, and delayed nuclear fusion during mating. Studies of related genes in other species link the family to reduced virulence and oxidative stress response.