BD — Magnaporthe oryzae 70-15

Summary

MGG_09499 (MoBD) on chromosome 3 of Magnaporthe oryzae 70-15 encodes a small GTPase of the Ras-type family, possessing GTPase activity, GTP binding, and G protein activity. The gene is associated with a wide range of biological processes including Ras protein signal transduction, the MAPK cascade, regulation of conidium formation, appressorium formation, invasive growth, sporulation, hyphal growth, melanin anabolism, programmed cell death, deubiquitination, vacuolar transport, secretion, and morphogenesis. It is linked to the plasma membrane. Phenotypic associations include decreased vacuolar transport rate, absent bipolar budding, decreased redox state, increased mating-type switching, decreased entry into G0, absent osmotic and oxidative stress resistance, delayed nuclear export, abnormal pheromone production, increased protein transport, and decreased flocculation. Studies of related genes in other species link the family to reduced virulence and oxidative stress response.