scd1 — Magnaporthe oryzae 70-15

Summary

MGG_09697 (scd1) on chromosome 4 of Magnaporthe oryzae 70-15 encodes a Rho guanine nucleotide exchange factor with a DH domain, a PH domain, and a PB1 domain, and is annotated with lipid binding. This gene is associated with appressorium formation, host invasion, sporulation, pigmentation, melanin anabolism, cell wall biogenesis, septin ring organization, division septum assembly, regulation of mitotic spindle organization, endocytosis, and establishment or maintenance of bipolar cell polarity. The encoded protein localizes to the cell tip, cleavage furrow, division septum, mitotic spindle, and mating projection tip. Studies of related genes in other species link the family to Cdc42 GTPase complex localization and, more distantly, to germination rate and oxidative stress response.