SWI6 — Magnaporthe oryzae 70-15

Summary

MoSWI6 (MGG_09869) on chromosome 6 of Magnaporthe oryzae 70-15 encodes a protein containing KilA/APSES-type HTH and ankyrin repeat domains. The protein exhibits promoter-specific chromatin binding, DNA-binding transcription repressor and activator activities for RNA polymerase II, transcription coactivator activity, and sequence-specific DNA binding. MoSWI6 is associated with the SBF and MBF complexes, localizes to chromatin, cytoplasm, cytosol, and nucleus, and is linked to cell cycle control, meiotic cell cycle modulation, hyphal growth, conidia and spore formation, melanin anabolism, morphogenesis, and steroid metabolism. It is associated with rice blast and turgor pressure. Related genes in other species link the family to oxidative stress response and protein content.