SHD1 — Magnaporthe oryzae 70-15

Summary

MGG_09964 (MoSHD1) on chromosome 4 of Magnaporthe oryzae 70-15 encodes an uncharacterized protein. The gene is associated with appressorium formation, invasive growth, endocytosis, clathrin-mediated endocytosis (CME), and autophagy. Phenotypic associations include abnormal spore germination, delayed vegetative growth, absent septum formation and cell fusion, altered budding patterns, increased gamma ray and hydrostatic pressure resistance, and abnormal filamentous growth, vesicle distribution, and plasma membrane morphology. The gene is also linked to altered rates of cytokinesis, protein transport, intracellular transport, pexophagy, micronucleophagy, and nuclear transport, as well as decreased mitotic recombination and increased entry into G0 phase. Related genes in other species include SLA1, which is associated with endocytic adaptor functions and interactions with proteins such as Las17, Ark1, and Bbc1.