slp1 — Magnaporthe oryzae 70-15

Summary

MGG_10097 (slp1) on chromosome 4 of Magnaporthe oryzae 70-15 encodes a protein with a LysM domain that exhibits lytic endotransglycosylase activity, PAMP receptor decoy activity, and chitin binding. The gene is associated with effector-mediated suppression of host pattern-triggered immunity, innate immunity, ER-phagy, and secretion. The product localizes to the hyphal cell wall and extracellular space. Associations with barley and rice blast disease have been noted, as well as a connection to turgor pressure. Related genes in other species link the LysM-containing protein family to virulence in tomato leaf mold, wheat septoria tritici blotch, and fusarium wilt, and to the proteins ECP6, Mg3LysM, ELP1, ELP2, CIH1, and slp2.