DBP2 — Magnaporthe oryzae 70-15

Summary

MoDBP2 (MGG_10312) on chromosome 7 of Magnaporthe oryzae 70-15 encodes a DEAD-box RNA helicase with ATP hydrolase, RNA helicase, G-quadruplex binding, RNA strand annealing, and identical protein binding activities. The gene is associated with mitochondrial RNA processing, including group I and II intron splicing, mRNA processing, translation elongation and initiation, and rRNA maturation. It is linked to sexual reproduction, mating, and digestion. The protein localises to mitochondria, the mitochondrial ribosome and lumen, the nucleolus, nuclear envelope, and preribosome. Phenotypic associations include abnormal mitotic recombination, decreased mating-type switching, absent or abnormal sporulation efficiency, altered cell cycle progression (increased G1/S and S phase rates, delayed G2/M and anaphase), delayed vegetative and exponential growth, increased thermotolerance and gamma ray resistance, altered chemical resistance, and increased fermentative growth and carbon source utilisation.