PPOA — Magnaporthe oryzae 70-15

Summary

MGG_10859 (PPOA) on chromosome 3 of Magnaporthe oryzae 70-15 encodes a haem peroxidase-domain protein with linoleate 8R-lipoxygenase, 9,12-octadecadienoate 8-hydroperoxide 8S-isomerase, fatty acid peroxidase, dioxygenase, isomerase, monooxygenase and oxidoreductase activities, and binds iron and haem. The gene is associated with oxylipin and prostaglandin anabolism, ferroptosis, response to oxidative stress, hydrogen peroxide catabolism, and both positive regulation of asexual sporulation and negative regulation of sexual sporulation. It is also linked to appressorium formation, autophagy, and long-chain fatty acid, carboxylic acid, penicillin and sterigmatocystin anabolism. Studies of related genes in other species connect the family to hypervirulence and unaffected pathogenicity.