FLO8 — Magnaporthe oryzae 70-15

Summary

MGG_11346 (MoFLO8) encodes a protein containing a Gal11_coact domain, placing it in the Mediator complex subunit 15 family. In Magnaporthe oryzae, this gene is associated with flocculation, biofilm formation, pseudohyphal growth, filamentous growth, spore formation, and xenobiotic metabolism. It has been linked to blast disease in rice (Oryza sativa) and barley (Hordeum vulgare). Associations with numerous cell cycle phenotypes have been observed, including altered progression through G1, S, G2, and M phases, increased gamma ray and UV resistance, and abnormal axial budding and silencing. The gene is also associated with increased acid pH resistance, decreased mating response, and altered vegetative growth rates. Studies of related genes in other species link the family to DNA repair and cell cycle regulation.