GIT7 — Magnaporthe oryzae 70-15

Summary

MGG_11701 (MoGIT7) in Magnaporthe oryzae 70-15 encodes an SGT1 and CS domain-containing protein with chaperone protein binding activity. This gene is associated with appressorium maturation, the glucose-sensing PKA pathway, gluconeogenesis, phospholipid and lipid metabolism, protein folding, cell death, and virus-induced PTGS. The product localises to the cytoplasm, cytosol, and nucleus. Associations with phenotypes include increased nuclear import, abnormal meiotic recombination, cell cycle arrest at G1/S and G2/M transitions, delayed autophagy, absent pexophagy, increased starvation resistance, decreased mating response, abnormal chromosome segregation, and increased acid pH resistance. Related genes in other species link it to HSP90 co-chaperone function, kinetochore assembly, and cyclic AMP signalling.