MGG_12130 — Magnaporthe oryzae 70-15

Summary

MoPAR1 (MGG_12130) on chromosome 6 of Magnaporthe oryzae 70-15 encodes a PP2A B56 regulatory subunit, a member of the ARM-type fold protein family, with protein phosphatase activator and regulator activity, protein-binding bridging, and DNA-binding functions. The gene is associated with appressorium formation, pigmentation, cell cycle modulation including mitotic G1 cell size control and septation initiation signaling, nuclear chromosome segregation, meiotic sister chromatid cohesion, septin ring disassembly, and protein localization to chromosomes. It localizes to the PP2A complex, kinetochore, centromere complex, meiotic spindle, spindle pole body, mitotic actomyosin contractile ring, and cellular bud neck. Phenotypic associations include decreased autophagy and pexophagy rates, altered cell cycle progression, abnormal sporulation efficiency, decreased hypoosmotic stress resistance, and absent alkaline pH resistance and X-ray resistance.