AOX — Magnaporthe oryzae 70-15

Summary

MGG_12936, designated AOX1 (synonyms AOX, MoAOX, MoAOD-1, MoAOD-3, MoAOX1, MoAOX2), encodes an alternative oxidase in Magnaporthe oryzae 70-15 on chromosome 3. The product belongs to the AOX superfamily and possesses alternative oxidase activity, a metal-binding enzyme classified under EC 1.-.-.-. This protein localises to the mitochondrial inner membrane and is associated with alternative respiration and electron transfer. The gene is linked to the oxidative stress response, a trait inferred from related genes in other species. Sequence similarity connections to orthologs in Verticillium dahliae and Fusarium oxysporum strains further associate the AOX family with stress tolerance pathways, though these relationships are not directly established in M. oryzae.