PPOA — Magnaporthe oryzae 70-15

Summary

MGG_13239 (PPOA) on chromosome 3 of Magnaporthe oryzae 70-15 encodes a protein with a Ppo-like N-terminal domain and animal haem peroxidase and cytochrome P450 domains, possessing linoleate 8R-lipoxygenase, 9,12-octadecadienoate 8-hydroperoxide 8S-isomerase, fatty acid peroxidase, peroxidase, dioxygenase, isomerase, monooxygenase, and oxidoreductase activities, and binding heme and iron. This gene is associated with oxylipin and prostaglandin biosynthesis, ferroptosis, appressorium formation, asexual and sexual sporulation, autophagy, oxidative stress response, hydrogen peroxide catabolism, and fatty acid, lipid, carboxylic acid, penicillin, and sterigmatocystin metabolism. It is linked to rice blast disease. Studies of related genes in other species connect the family to altered virulence.