ABC2 — Magnaporthe oryzae 70-15

Summary

MoABC2 (MGG_13762) on chromosome 1 of Magnaporthe oryzae 70-15 encodes an ABC-type oligopeptide transporter with ATP-coupled transmembrane transporter activity and ATP hydrolase activity, belonging to the type 1 exporter family. The gene is associated with oligopeptide export from the mitochondrion, host invasion, invasive growth, morphogenesis, autophagy, secondary metabolism, cell wall biogenesis, signal transduction, and siRNA-mediated post-transcriptional gene silencing. It localises to the mitochondrial inner membrane, endomembrane system, and plasmalemma. Phenotypic associations include abnormal cell cycle progression, decreased hyperosmotic and hypo-osmotic stress resistance, altered vacuolar morphology, increased pexophagy, and abnormal colony color. Studies of related genes in other species link the family to loss of pathogenicity.