SCH9 — Magnaporthe oryzae 70-15

Summary

MoSCH9 (MGG_14773) on chromosome 2 of Magnaporthe oryzae 70-15 encodes a non-specific serine/threonine protein kinase with AGC-kinase and C2 domains, annotated with protein kinase C activity, protein serine/threonine kinase activity, lipid binding, zinc binding, and ATP binding. The gene is associated with diverse biological processes including positive regulation of the cell integrity MAPK cascade, regulation of sphingolipid biosynthesis, downregulation of TORC2 signaling, positive regulation of ribosomal protein gene transcription, and regulation of cell wall glucan biosynthesis. It is linked to downregulation of host gene-for-gene resistance by the symbiont and regulation of response to osmotic stress. Localization evidence connects the product to the cytoskeleton, division septum, cell tip, stress granule, and nuclear envelope. Phenotypic associations include altered spore germination, increased thermotolerance, absent oxidative stress resistance, and abnormal replicative lifespan.