CDA — Magnaporthe oryzae 70-15

Summary

MGG_14966 (CDA) on chromosome 6 of Magnaporthe oryzae 70-15 encodes a chitin deacetylase, a hydrolase acting on carbon-nitrogen bonds, with chitin-binding, zinc-binding and metal-binding activities. The protein contains NodB, glycosyl hydrolase/deacetylase and chitin-binding domains. It is associated with appressorium formation, immune evasion, chitin and polysaccharide breakdown, fungal-type cell wall biogenesis and organization, carbohydrate metabolism, morphogenesis, and cell death. The product localizes to the vacuole, side of membrane, fungal-type cell wall, extracellular region, and plasmalemma. The gene is also linked to turgor pressure. Studies of related genes in other species connect the family to reduced virulence and unaffected pathogenicity, as well as to hosts including rice, maize, and mouse.